FDA cleared first-ever glucose monitoring system for weight loss from Signos

Signos

August, 2025

The FDA has cleared the first glucose monitoring system designed specifically for weight management, developed by our partner, Signos. Unlike existing treatments such as GLP-1 drugs or bariatric surgery—which are often limited to patients with obesity—Signos’ system is available to anyone through a membership program. It combines an AI-powered platform with a Dexcom continuous glucose monitor (CGM) to provide real-time insights and personalized recommendations for healthier weight management.

This clearance offers a more accessible and affordable option compared to costly obesity drugs, which can exceed $1,000 per month and face supply challenges. With plans starting at $129 per month, Signos provides CGMs, app-based tracking, and tailored guidance to support weight goals. The system can also complement existing treatments, helping patients maintain progress after GLP-1 therapy or surgery. By bringing metabolic data to everyday users, Signos aims to help millions better understand their bodies and achieve long-term, sustainable weight management.